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Novel regulation of miR‐34a‐5p and HOTAIR by the combination of berberine and gefitinib  leading to inhibition of EMT in human lung cancer

HOTAIR is an important carcinogenic lncRNA and involves in tumorigenesis, and invasion. MiR‐34a‐5p functions as a tumour suppressor. However, the underlying mechanism of HOTAIR regulation especially in association with miR‐34a‐5p in non‐small‐cell lung cancer (NSCLC) has not been explored. Herein, w...

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Podrobná bibliografie
Vydáno v:J Cell Mol Med
Hlavní autoři: Zheng, Fang, Li, Jing, Ma, ChangJu, Tang, XiaoJuan, Tang, Qing, Wu, JingJing, Chai, XiaoSu, Xie, Jianhui, Yang, Xiao‐bo, Hann, Swei Sunny
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214156/
https://ncbi.nlm.nih.gov/pubmed/32248643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15214
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