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Mechanistic Links between Obesity, Insulin, and Cancer

Obesity and type 2 diabetes (T2D) increase the prevalence and worsen the prognosis of more than a dozen tumor types; however, the mechanism for this association remains hotly debated. Here we discuss a potential role for insulin as the key hormonal mediator of tumor metabolism and growth in obesity-...

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Publicat a:Trends Cancer
Autors principals: Perry, Rachel J., Shulman, Gerald I.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7214048/
https://ncbi.nlm.nih.gov/pubmed/32061306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2019.12.003
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