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Integrating Mechanisms for Insulin Resistance: Common Threads and Missing Links

Insulin resistance is a complex metabolic disorder that defies a single etiological pathway. Accumulation of ectopic lipid metabolites, activation of the unfolded protein response (UPR) pathway and innate immune pathways have all been implicated in the pathogenesis of insulin resistance. However, th...

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Detalhes bibliográficos
Main Authors: Samuel, Varman T., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294420/
https://ncbi.nlm.nih.gov/pubmed/22385956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.017
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