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Aptamer-functionalized Hybrid Nanoparticles to Enhance the Delivery of Doxorubicin into Breast Cancer Cells by Silencing P-glycoprotein
OBJECTIVE: The MDR of metastatic breast cancer cells is accompanied by the overexpression of P-gp transporter. This study has been focused to determine whether silencing the expression of P-gp by aptamer-labeled siRNA nanoparticles could enhance the delivery of doxorubicin into breast cancer cells i...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cancer Treatment Diagn |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7213597/ https://ncbi.nlm.nih.gov/pubmed/32395707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29245/2578-2967/2020/1.1176 |
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