Integrating Multiple Biomarkers to Increase Sensitivity for the Detection of Onchocerca volvulus Infection

BACKGROUND: Serological assessments for human onchocerciasis are based on IgG4 reactivity against the OV-16 antigen, with sensitivities of 60-80%. We have previously identified 7 novel proteins that could improve serodiagnosis. METHODS: IgG4 responses to these 7 proteins were assessed by luciferase...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Bennuru, Sasisekhar, Oduro-Boateng, Georgiette, Osigwe, Chinweoke, Del Valle, Priscilla, Golden, Allison, Ogawa, Guilherme Maerschner, Cama, Vitaliano, Lustigman, Sara, Nutman, Thomas B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213562/
https://ncbi.nlm.nih.gov/pubmed/31201416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz307
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