CBMS-05 COMPREHENSIVE METABOLOMIC ANALYSIS OF IDH1R132H CLINICAL GLIOMA SAMPLES REVEALS SUPPRESSION OF Β-OXIDATION DUE TO CARNITINE DEFICIENCY

BACKGROUND: Gliomas with isocitrate dehydrogenase 1 (IDH1) mutation have alterations in several enzyme activities, resulting in various metabolic changes. The aim of this study was to investigate the mechanism for the better prognosis of gliomas with IDH mutation by performing metabolomic analysis....

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Miyata, Satsuki, Tominaga, Kaoru, Sakashita, Eiji, Urabe, Masashi, Onuki, Yoshiyuki, Gomi, Akira, Yamaguchi, Takashi, Mieno, Makiko, Mizukami, Hiroaki, Kume, Akihiro, Ozawa, Keiya, Watanabe, Eijyu, Kawai, Kensuke, Endou, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213357/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz039.025
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