MLTI-01. IMMUNOLOGICAL REPROGRAMMING IN THE CNS TUMOR MICROENVIRONMENT AND THERAPEUTIC EFFICACY OF RADIOTHERAPY WITH STAT3 BLOCKADE

BACKGROUND: Patients with central nervous system (CNS) tumors are typically treated with radiation therapy, but this is not curative and results in the upregulation of p-STAT3 that drives invasion, angiogenesis, and immune suppression. Therefore, we investigated the combined effect of an inhibitor o...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Ott, Martina, Hashimoto, Yuuri, Marisetty, Anantha, Wei, Jun, Zamler, Daniel, Leu, Jia-Shiun, Kong, Ling-Yuan, Zhou, Shouhao, Fuller, Gregory, de Groot, John, Priebe, Waldemar, Sulman, Erik, Heimberger, Amy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213227/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.060
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