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Endorepellin evokes an angiostatic stress signaling cascade in endothelial cells
Endorepellin, the C-terminal fragment of the heparan sulfate proteoglycan perlecan, influences various signaling pathways in endothelial cells by binding to VEGFR2. In this study, we discovered that soluble endorepellin activates the canonical stress signaling pathway consisting of PERK, eIF2α, ATF4...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7212646/ https://ncbi.nlm.nih.gov/pubmed/32205445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012525 |
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