Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

BACKGROUND: Ubiquitously expressed CTCF is involved in numerous cellular functions, such as organizing chromatin into TAD structures. In contrast, its paralog, CTCFL, is normally only present in the testis. However, it is also aberrantly expressed in many cancers. While it is known that shared and u...

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Vydáno v:Genome Biol
Hlavní autoři: Nishana, Mayilaadumveettil, Ha, Caryn, Rodriguez-Hernaez, Javier, Ranjbaran, Ali, Chio, Erica, Nora, Elphege P., Badri, Sana B., Kloetgen, Andreas, Bruneau, Benoit G., Tsirigos, Aristotelis, Skok, Jane A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212617/
https://ncbi.nlm.nih.gov/pubmed/32393311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02024-0
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