Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

BACKGROUND: Ubiquitously expressed CTCF is involved in numerous cellular functions, such as organizing chromatin into TAD structures. In contrast, its paralog, CTCFL, is normally only present in the testis. However, it is also aberrantly expressed in many cancers. While it is known that shared and u...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Nishana, Mayilaadumveettil, Ha, Caryn, Rodriguez-Hernaez, Javier, Ranjbaran, Ali, Chio, Erica, Nora, Elphege P., Badri, Sana B., Kloetgen, Andreas, Bruneau, Benoit G., Tsirigos, Aristotelis, Skok, Jane A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212617/
https://ncbi.nlm.nih.gov/pubmed/32393311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02024-0
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