Chromatin topology reorganization and transcription repression by PML-RARα in acute promyeloid leukemia

BACKGROUND: Acute promyeloid leukemia (APL) is characterized by the oncogenic fusion protein PML-RARα, a major etiological agent in APL. However, the molecular mechanisms underlying the role of PML-RARα in leukemogenesis remain largely unknown. RESULTS: Using an inducible system, we comprehensively...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Wang, Ping, Tang, Zhonghui, Lee, Byoungkoo, Zhu, Jacqueline Jufen, Cai, Liuyang, Szalaj, Przemyslaw, Tian, Simon Zhongyuan, Zheng, Meizhen, Plewczynski, Dariusz, Ruan, Xiaoan, Liu, Edison T., Wei, Chia-Lin, Ruan, Yijun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212609/
https://ncbi.nlm.nih.gov/pubmed/32393309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02030-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados