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3D-GNOME 2.0: a three-dimensional genome modeling engine for predicting structural variation-driven alterations of chromatin spatial structure in the human genome

Structural variants (SVs) that alter DNA sequence emerge as a driving force involved in the reorganisation of DNA spatial folding, thus affecting gene transcription. In this work, we describe an improved version of our integrated web service for structural modeling of three-dimensional genome (3D-GN...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wlasnowolski, Michal, Sadowski, Michal, Czarnota, Tymon, Jodkowska, Karolina, Szalaj, Przemyslaw, Tang, Zhonghui, Ruan, Yijun, Plewczynski, Dariusz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319547/
https://ncbi.nlm.nih.gov/pubmed/32442297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa388
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