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High tumor mutation burden is associated with DNA damage repair gene mutation in breast carcinomas
BACKGROUND: Immunotherapy has demonstrated encouraging clinical benefits in patients with advanced breast carcinomas and Programmed death ligand 1 (PD-L1) expression has been proposed as an immunotherapy biomarker. Challenges with current PD-L1 testing exist and tumor mutation burden (TMB) is emergi...
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| Publicado no: | Diagn Pathol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7212599/ https://ncbi.nlm.nih.gov/pubmed/32393302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-020-00971-7 |
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