Effects of long-acting GIP, xenin and oxyntomodulin peptide analogues on alpha-cell transdifferentiation in insulin-deficient diabetic Glu(CreERT2);ROSA26-eYFP mice

Enzyme-resistant long-acting forms of the gut-derived peptide hormones, glucose-dependent insulinotropic polypeptide (GIP), xenin and oxyntomodulin (Oxm) have been generated, and exert beneficial effects on diabetes control and pancreatic islet architecture. The current study has employed alpha-cell...

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Publicado en:Peptides
Main Authors: Sarnobat, Dipak, Moffett, R. Charlotte, Gault, Victor A., Tanday, Neil, Reimann, Frank, Gribble, Fiona M., Flatt, Peter R., Irwin, Nigel
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212078/
https://ncbi.nlm.nih.gov/pubmed/31738969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2019.170205
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