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Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells

GLUTag, NCI-H716 and STC-1 are cell lines that are widely used to study mechanisms underlying secretion of glucagon-like peptide (GLP-1), but the extent to which they resemble native L-cells is unknown. We used validated immunoassays for 14 different hormones to analyze peptide content (lysis sample...

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Detalhes bibliográficos
Publicado no:J Mol Endocrinol
Main Authors: Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F, Balk-Møller, Emilie, Rehfeld, Jens F., Reimann, Frank, Gribble, Fiona Mary, Holst, Jens Juul
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212058/
https://ncbi.nlm.nih.gov/pubmed/26819328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-15-0293
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