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Moderation of mitochondrial respiration mitigates metabolic syndrome of aging

Deregulation of mitochondrial dynamics leads to the accumulation of oxidative stress and unhealthy mitochondria; consequently, this accumulation contributes to premature aging and alterations in mitochondria linked to metabolic complications. We postulate that restrained mitochondrial ATP synthesis...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tavallaie, Mojdeh, Voshtani, Ramouna, Deng, Xinxian, Qiao, Yixue, Jiang, Faqin, Collman, James P., Fu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211973/
https://ncbi.nlm.nih.gov/pubmed/32303655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917948117
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