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GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats

The glucagon-like peptide-1 receptor (GLP-1R) agonist liraglutide is approved for the treatment of obesity; however, there is still much to be learned regarding the neuronal sites of action that underlie its suppressive effects on food intake and body weight. Peripherally administered liraglutide in...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Fortin, Samantha M., Lipsky, Rachele K., Lhamo, Rinzin, Chen, Jack, Kim, Eun, Borner, Tito, Schmidt, Heath D., Hayes, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211411/
https://ncbi.nlm.nih.gov/pubmed/32132220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aay8071
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