A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Depression is a leading cause of worldwide disability but there remains considerable uncertainty regarding its neural and behavioural associations. Here, using non-overlapping Psychiatric Genomics Consortium (PGC) datasets as a reference, we estimate polygenic risk scores for depression (depression-...

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Udgivet i:Nat Commun
Main Authors: Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Deary, Ian J., Whalley, Heather C., McIntosh, Andrew M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210889/
https://ncbi.nlm.nih.gov/pubmed/32385265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16022-0
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