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A Sequential Umpolung/Enzymatic Dynamic Kinetic Resolution Strategy for the Synthesis of γ-Lactones

Combining biological and small-molecule catalysts under a chemoenzymatic manifold presents a series of significant advantages to the synthetic community. We report herein the successful development of a two-step/single flask synthesis of γ-lactones through the merger of Umpolung catalysis with a ket...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Maskeri, Mark A., Schrader, Malte L., Scheidt, Karl A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7210063/
https://ncbi.nlm.nih.gov/pubmed/32084294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000747
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