Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment

In solid tumors, increasing drug penetration promotes their regression and improves the therapeutic index of compounds. However, the heterogeneous extracellular matrix (ECM) acts as a steric and interaction barrier that hinders effective transport of therapeutics, including nanomedicines. Specifical...

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Detaylı Bibliyografya
Yayımlandı:Nanoscale
Asıl Yazarlar: Mohanty, Rashmi P., Liu, Xinquan, Kim, Jae Y., Peng, Xiujuan, Bhandari, Sahil, Leal, Jasmim, Arasappan, Dhivya, Wylie, Dennis, Dong, Tony, Ghosh, Debadyuti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209769/
https://ncbi.nlm.nih.gov/pubmed/31536061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr05783h
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