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Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment

In solid tumors, increasing drug penetration promotes their regression and improves the therapeutic index of compounds. However, the heterogeneous extracellular matrix (ECM) acts as a steric and interaction barrier that hinders effective transport of therapeutics, including nanomedicines. Specifical...

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Publicado en:Nanoscale
Main Authors: Mohanty, Rashmi P., Liu, Xinquan, Kim, Jae Y., Peng, Xiujuan, Bhandari, Sahil, Leal, Jasmim, Arasappan, Dhivya, Wylie, Dennis, Dong, Tony, Ghosh, Debadyuti
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209769/
https://ncbi.nlm.nih.gov/pubmed/31536061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9nr05783h
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