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SUN-751 RORγ Is a Master Regulator of Tumor Lipid Metabolism

Lipid and cholesterol metabolism reprogramming is strongly linked to tumorigenesis and therapeutic resistance. Our recent genetic disruptions via CRISPR KO and gene silencing and pharmacological inhibition clearly demonstrated that nuclear receptor RORγ plays a crucial role in control of lipid and c...

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Bibliografske podrobnosti
izdano v:J Endocr Soc
Glavni avtor: Chen, Hong-Wu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209691/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.692
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