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MON-LB57 Impact of Imputation Method and Response Cutoffs on Results From the Phase 3 OPTIMAL Study of Oral Octreotide Capsules in Adult Patients With Acromegaly

Objective: The phase 3 CHIASMA OPTIMAL study assessed efficacy and safety of oral octreotide capsules (OOC) in patients with acromegaly controlled on injectable somatostatin receptor ligands (SRLs). Sensitivity analyses were conducted for efficacy endpoints using two methods of imputation (i.e., the...

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Bibliografski detalji
Izdano u:J Endocr Soc
Glavni autori: Samson, Susan Leanne, Nachtigall, Lisa B, Fleseriu, Maria, Gordon, Murray B, Jensterle, Mojca, Elenkova, Atanaska, Ludlam, William Henry, Patou, Gary, Haviv, Asi, Biermasz, Nienke, Trainer, Peter James, Strasburger, Christian Joseph, Kennedy, Laurence, Melmed, Shlomo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209634/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2120
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