MON-LB57 Impact of Imputation Method and Response Cutoffs on Results From the Phase 3 OPTIMAL Study of Oral Octreotide Capsules in Adult Patients With Acromegaly

Objective: The phase 3 CHIASMA OPTIMAL study assessed efficacy and safety of oral octreotide capsules (OOC) in patients with acromegaly controlled on injectable somatostatin receptor ligands (SRLs). Sensitivity analyses were conducted for efficacy endpoints using two methods of imputation (i.e., the...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Samson, Susan Leanne, Nachtigall, Lisa B, Fleseriu, Maria, Gordon, Murray B, Jensterle, Mojca, Elenkova, Atanaska, Ludlam, William Henry, Patou, Gary, Haviv, Asi, Biermasz, Nienke, Trainer, Peter James, Strasburger, Christian Joseph, Kennedy, Laurence, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Neuroendocrinology and Pituitary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209634/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2120
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