SAT-597 Hypothalamic ESR1 Gene Knockdown Elicits Intermittent Decrement in Postprandial Energy Expenditure Associated with Obesity Onset in Female Rhesus Monkeys

Declining serum estradiol (E(2)) levels during the menopausal transition are associated with increased central adiposity and heightened risk for metabolic disease. Estrogenic effects on adiposity and metabolism in female rodents are primarily mediated by estrogen receptor alpha (ESR1) activation in...

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Bibliografiska uppgifter
I publikationen:J Endocr Soc
Huvudupphovsmän: Willging, Molly, Levine, Jon E, Greinwald, Emily, Flowers, Matthew T, Colman, Ricki J, Abbott, David Howard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Adipose Tissue, Appetite, and Obesity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209601/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1807
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