SAT-597 Hypothalamic ESR1 Gene Knockdown Elicits Intermittent Decrement in Postprandial Energy Expenditure Associated with Obesity Onset in Female Rhesus Monkeys

Declining serum estradiol (E(2)) levels during the menopausal transition are associated with increased central adiposity and heightened risk for metabolic disease. Estrogenic effects on adiposity and metabolism in female rodents are primarily mediated by estrogen receptor alpha (ESR1) activation in...

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Vydáno v:J Endocr Soc
Hlavní autoři: Willging, Molly, Levine, Jon E, Greinwald, Emily, Flowers, Matthew T, Colman, Ricki J, Abbott, David Howard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Adipose Tissue, Appetite, and Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209601/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1807
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