OR11-03 NT-814, a Non-Hormonal Dual Neurokinin 1,3 Receptor Antagonist Markedly Improves Vasomotor Symptoms in Post-Menopausal Women; Results of a Randomised, Double-Blind, Placebo-Controlled, Dose-Finding Study (SWITCH-1)

Introduction: Vasomotor symptoms (VMS), caused by declining estrogen in menopausal women, are common and debilitating. Hormone therapy is effective in many women but carries risks and may be contraindicated. Biological and clinical evidence shows a modulatory role for neurokinin (NK) receptor antago...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Simon, James, Anderson, Richard A, Ballantyne, Elizabeth, Joffe, Hadine, Kerr, Mary, Seymore, Susan, Trower, Mike, Pawsey, Steve
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Reproductive Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209544/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2071
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