OR11-03 NT-814, a Non-Hormonal Dual Neurokinin 1,3 Receptor Antagonist Markedly Improves Vasomotor Symptoms in Post-Menopausal Women; Results of a Randomised, Double-Blind, Placebo-Controlled, Dose-Finding Study (SWITCH-1)

Introduction: Vasomotor symptoms (VMS), caused by declining estrogen in menopausal women, are common and debilitating. Hormone therapy is effective in many women but carries risks and may be contraindicated. Biological and clinical evidence shows a modulatory role for neurokinin (NK) receptor antago...

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Vydáno v:J Endocr Soc
Hlavní autoři: Simon, James, Anderson, Richard A, Ballantyne, Elizabeth, Joffe, Hadine, Kerr, Mary, Seymore, Susan, Trower, Mike, Pawsey, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Reproductive Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209544/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2071
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