OR28-04 Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates

Introduction: Receptor tyrosine kinases (RTKs) initiate signaling cascades, including growth and differentiation. Activation can occur through chromosomal rearrangements that lead to gene fusions. RTK fusions are potential targets for small molecule inhibitors to treat advanced cancers. The original...

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Pubblicato in:J Endocr Soc
Autori principali: Wirth, Lori J, Grubbs, Elizabeth G, Livhits, Masha J, Sherman, Steven I, Weitzman, Steven P, Dosiou, Chrysoula, Ladenson, Paul W, Hao, Yangyang, Babiarz, Joshua E, Kennedy, Giulia C, Kloos, Richard T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Thyroid
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209442/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2185
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