OR28-04 Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates

Introduction: Receptor tyrosine kinases (RTKs) initiate signaling cascades, including growth and differentiation. Activation can occur through chromosomal rearrangements that lead to gene fusions. RTK fusions are potential targets for small molecule inhibitors to treat advanced cancers. The original...

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Détails bibliographiques
Publié dans:J Endocr Soc
Auteurs principaux: Wirth, Lori J, Grubbs, Elizabeth G, Livhits, Masha J, Sherman, Steven I, Weitzman, Steven P, Dosiou, Chrysoula, Ladenson, Paul W, Hao, Yangyang, Babiarz, Joshua E, Kennedy, Giulia C, Kloos, Richard T
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Thyroid
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209442/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2185
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