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SUN-LB124 Novel Elisa Assays Demonstrate Specificity of Islet and Intestinal Processing of Proglucagon
Circulating proglucagon peptides (PGP) are produced in islet α-cells, enteroendocrine L-cells. Release of PGP is thought to be tissue specific, e.g. α-cells make glucagon and L-cells make GLP-1 through predominant actions of proconvertases 2 and 1/3 (PC2 and PC1/3). However, this dichotomous model h...
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| Publicat a: | J Endocr Soc |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7209030/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2330 |
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