SUN-131 The Roles of Two Insulin Receptor Isoforms in Triple Negative Breast Cancer Growth

Systemic hyperinsulinemia is believed to be an important factor in the progression of a number of cancers, including breast cancer by activating the insulin receptor (IR) signaling cascade in the tumor cells. The IR is expressed in two isoforms, IR-A and IR-B. IR-B is the full-length isoform, while...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Kang, Chifei, Shlomai, Gadi, James, Annie, Antoniou, Irini M, Scully, Tiffany, Ettela, Abora, Kase, Nathan G, Wood, Teresa, LeRoith, Derek, Gallagher, Emily Jane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Tumor Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208475/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1817
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