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OR26-01 Epinephrine Is Essential for Normal Renal Glucose Reabsorption via the Glucose Transporter GLUT2

Humans and mice with Melanocortin 4 receptor (MC4R) deficiency remain protected from hyperglycemia despite chronic obesity and insulin resistance. We have observed that elevated glycosuria in MC4R deficient mice protects them from hyperglycemia. Moreover, our results indicate that circulating epinep...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Elsheikh, Arwa Mahmoud, de Souza Cordeiro, Leticia M, Devisetty, Nagavardhini, Ebert, Steven N, Chhabra, Kavaljit H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208471/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.524
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