OR26-01 Epinephrine Is Essential for Normal Renal Glucose Reabsorption via the Glucose Transporter GLUT2

Humans and mice with Melanocortin 4 receptor (MC4R) deficiency remain protected from hyperglycemia despite chronic obesity and insulin resistance. We have observed that elevated glycosuria in MC4R deficient mice protects them from hyperglycemia. Moreover, our results indicate that circulating epinep...

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Bibliografski detalji
Izdano u:J Endocr Soc
Glavni autori: Elsheikh, Arwa Mahmoud, de Souza Cordeiro, Leticia M, Devisetty, Nagavardhini, Ebert, Steven N, Chhabra, Kavaljit H
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Diabetes Mellitus and Glucose Metabolism
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208471/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.524
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