SAT-LB72 Design of the PaTH Forward Phase 2 Trial of TransCon PTH, a Long-Acting PTH, in Patients With Hypoparathyroidism

Background: Hypoparathyroidism (HP) is caused by a deficiency in parathyroid hormone (PTH), which leads to hypocalcemia and hyperphosphatemia. Standard of care (SoC), i.e. large doses of calcium (Ca) and active vitamin D, worsens hypercalciuria and increases the serum Ca (sCa) x serum phosphate (sP)...

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Bibliografiska uppgifter
I publikationen:J Endocr Soc
Huvudupphovsmän: Khan, Aliya Aziz, Rejnmark, Lars, Schwarz, Peter E, Vokes, Tamara J, Clarke, Bart Lyman, Rubin, Mishaela Ruth, Hofbauer, Lorenz C, Erikson, Erik, Palermo, Andrea, Pagotto, Uberto, Marcocci, Claudio, Ahmed, Intekhab, Mourya, Sanchita, Markova, Denka, Karpf, David B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Bone and Mineral Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208407/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2209
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