SAT-LB72 Design of the PaTH Forward Phase 2 Trial of TransCon PTH, a Long-Acting PTH, in Patients With Hypoparathyroidism

Background: Hypoparathyroidism (HP) is caused by a deficiency in parathyroid hormone (PTH), which leads to hypocalcemia and hyperphosphatemia. Standard of care (SoC), i.e. large doses of calcium (Ca) and active vitamin D, worsens hypercalciuria and increases the serum Ca (sCa) x serum phosphate (sP)...

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Détails bibliographiques
Publié dans:J Endocr Soc
Auteurs principaux: Khan, Aliya Aziz, Rejnmark, Lars, Schwarz, Peter E, Vokes, Tamara J, Clarke, Bart Lyman, Rubin, Mishaela Ruth, Hofbauer, Lorenz C, Erikson, Erik, Palermo, Andrea, Pagotto, Uberto, Marcocci, Claudio, Ahmed, Intekhab, Mourya, Sanchita, Markova, Denka, Karpf, David B
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Bone and Mineral Metabolism
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208407/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2209
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