MON-199 Targeting Pheochromocytoma/Paraganglioma with Polyamine Inhibitors

Background: Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors that are mostly benign. Metastatic disease occurs in about 10% of cases, and for these patients no effective therapies are available. Patients with mutations in the succinate dehydrogenase subunit B (SDHB) gene...

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Vydáno v:J Endocr Soc
Hlavní autoři: Ghayee, Hans Kumar, Rai, Sudhir, Bril, Fernando, Hatch, Heather, Xu, Yiling, Kalavalapalli, Srilaxami, Garrett, Timothy, Plant, Dan, Bose, Prodip, Hromas, Robert, Cusi, Kenneth, Tischler, Arthur, Gupta, Priyanaka, Bibb, James, Beuschlein, Felix, Robledo, Mercedes, Calsina, Bruna, Timmers, Henri, Taieb, David, Kroiss, Matthias, Richter, Susan, Eisenhofer, Graeme, Bergeron, Raymond, Pacak, Karel, Tevosian, Sergei G
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Adrenal
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208096/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1165
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