MON-199 Targeting Pheochromocytoma/Paraganglioma with Polyamine Inhibitors

Background: Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors that are mostly benign. Metastatic disease occurs in about 10% of cases, and for these patients no effective therapies are available. Patients with mutations in the succinate dehydrogenase subunit B (SDHB) gene...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Ghayee, Hans Kumar, Rai, Sudhir, Bril, Fernando, Hatch, Heather, Xu, Yiling, Kalavalapalli, Srilaxami, Garrett, Timothy, Plant, Dan, Bose, Prodip, Hromas, Robert, Cusi, Kenneth, Tischler, Arthur, Gupta, Priyanaka, Bibb, James, Beuschlein, Felix, Robledo, Mercedes, Calsina, Bruna, Timmers, Henri, Taieb, David, Kroiss, Matthias, Richter, Susan, Eisenhofer, Graeme, Bergeron, Raymond, Pacak, Karel, Tevosian, Sergei G
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Adrenal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208096/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1165
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