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SAT-549 Identification of Somatic Mutations in CLCN2 as a Cause of Aldosterone-Producing Adenomas

Background: Primary aldosteronism (PA) results from both unilateral and bilateral adrenal disease. Unilateral disease is most often caused by aldosterone-producing adenomas (APAs). We recently identified aldosterone-driver somatic mutations in approximately 90% of APAs using an aldosterone synthase...

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Bibliografske podrobnosti
izdano v:J Endocr Soc
Main Authors: Rege, Juilee, Nanba, Kazutaka, Blinder, Amy R, Else, Tobias, Tomlins, Scott, Vats, Pankaj, Kumar-Sinha, Chandan, Giordano, Thomas J, Rainey, William E
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207880/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.1782
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