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Somatic CACNA1H mutation as a cause of aldosterone-producing adenoma

Driver somatic mutations for aldosterone excess have been found in approximately 90% of aldosterone-producing adenomas (APAs) using an aldosterone synthase (CYP11B2)-guided sequencing approach. In the present study, we identified a novel somatic CACNA1H mutation (c.T4289C, p.I1430T) in an APA withou...

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Bibliografski detalji
Izdano u:Hypertension
Glavni autori: Nanba, Kazutaka, Blinder, Amy R., Rege, Juilee, Hattangady, Namita G., Else, Tobias, Liu, Chia-Jen, Tomlins, Scott A., Vats, Pankaj, Kumar-Sinha, Chandan, Giordano, Thomas J., Rainey, William E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059016/
https://ncbi.nlm.nih.gov/pubmed/31983310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14349
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