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SUN-593 Variants in Known Monogenic Causal Genes of Hypertriglyceridemia Are Not Major Contributors for Hypertriglyceridemia in Lipodystrophy Due to a LMNA Mutation

Background: Lipodystrophy is a heterogeneous disorder of adiposity, and one common lipid manifestation is hypertriglyceridemia (HTG). The LMNA gene, which encodes for nuclear envelope proteins, is a known causal gene for heritable lipodystrophy. At present, underlying mechanisms for each clinical ma...

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Publié dans:J Endocr Soc
Auteurs principaux: Ueda, Masako, McIntyre, Adam D, Remaley, Alan T, Hegele, Robert A, Rader, Daniel J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207791/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.103
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