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SAT-421 Novel Role of Chloroquine and Hydroxychloroquine in Graves’ Orbitopathy Therapy by Targeting Orbital Fibroblasts
Abstract: Context: Graves’ orbitopathy (GO) presents with infiltrative exophthalmos due to excessive proliferation, adipogenesis and glycosaminoglycans production of orbital fibroblasts (OFs). There are few therapies potent for proptosis. Intervention in autophagy of OFs could be a potential therapy...
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| 出版年: | J Endocr Soc |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7207710/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.016 |
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