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Novel Roles of Chloroquine and Hydroxychloroquine in Graves’ Orbitopathy Therapy by Targeting Orbital Fibroblasts
CONTEXT: Graves’ orbitopathy (GO) causes infiltrative exophthalmos by inducing excessive proliferation, adipogenesis, and glycosaminoglycan production in orbital fibroblasts (OFs). Interference with OF autophagy is a potential therapy for proptosis. OBJECTIVES: Here, we aimed to evaluate the effects...
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| Publicado no: | J Clin Endocrinol Metab |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183395/ https://ncbi.nlm.nih.gov/pubmed/32249902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa161 |
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