Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection

The phenotypic and functional dichotomy between IRF8(+) type 1 and IRF4(+) type 2 conventional dendritic cells (cDC1s and cDC2s, respectively) is well accepted; it is unknown how robust this dichotomy is under inflammatory conditions, when additionally monocyte-derived cells (MCs) become competent a...

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Udgivet i:Immunity
Main Authors: Bosteels, Cedric, Neyt, Katrijn, Vanheerswynghels, Manon, van Helden, Mary J., Sichien, Dorine, Debeuf, Nincy, De Prijck, Sofie, Bosteels, Victor, Vandamme, Niels, Martens, Liesbet, Saeys, Yvan, Louagie, Els, Lesage, Manon, Williams, David L., Tang, Shiau-Choot, Mayer, Johannes U., Ronchese, Franca, Scott, Charlotte L., Hammad, Hamida, Guilliams, Martin, Lambrecht, Bart N.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207120/
https://ncbi.nlm.nih.gov/pubmed/32392463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.04.005
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