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Nrf2 activation through the inhibition of Keap1-Nrf2 protein-protein interaction
Activation of the transcription factor Nrf2 via the Keap1-Nrf2-ARE signaling system regulates the transcription and subsequent expression of cellular cytoprotective proteins and plays a crucial role in preventing pathological conditions exacerbated by the overproduction of oxidative stress. In addit...
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| Publicado no: | Med Chem Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7207041/ https://ncbi.nlm.nih.gov/pubmed/32390710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-020-02539-y |
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