A carregar...
Activation of NRF2 Signaling in HEK293 Cells by a First-In-Class Direct KEAP1-NRF2 Inhibitor
Under basal conditions, the antioxidant transcription factor NRF2 is bound to the KEAP1 protein and targeted for proteasomal degradation in the cytoplasm. In response to cellular injury or chemical treatment, NRF2 dissociates from KEAP1 and activates the transcription of protective genes and defends...
Na minha lista:
| Publicado no: | J Biochem Mol Toxicol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713195/ https://ncbi.nlm.nih.gov/pubmed/25683455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbt.21693 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|