Therapeutic Vaccine for Genital Herpes Simplex Virus-2 Infection: Findings From a Randomized Trial

BACKGROUND. Genital herpes simplex virus type 2 (HSV-2) infection causes recurrent lesions and frequent viral shedding. GEN-003 is a candidate therapeutic vaccine containing HSV-2 gD2∆TMR and ICP4.2, and Matrix-M2 adjuvant. METHODS. Persons with genital herpes were randomized into 3 dose cohorts to...

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Vydáno v:J Infect Dis
Hlavní autoři: Bernstein, David I., Wald, Anna, Warren, Terri, Fife, Kenneth, Tyring, Stephen, Lee, Patricia, Van Wagoner, Nick, Magaret, Amalia, Flechtner, Jessica B., Tasker, Sybil, Chan, Jason, Morris, Amy, Hetherington, Seth
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206854/
https://ncbi.nlm.nih.gov/pubmed/28329211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix004
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