CSNAP, the smallest CSN subunit, modulates proteostasis through cullin-RING ubiquitin ligases

The cullin-RING ubiquitin E3 ligase (CRL) family consists of ~250 complexes that catalyze ubiquitylation of proteins to achieve cellular regulation. All CRLs are inhibited by the COP9 signalosome complex (CSN) through both enzymatic (deneddylation) and nonenzymatic (steric) mechanisms. The relative...

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Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Füzesi-Levi, Maria G., Fainer, Irit, Ivanov Enchev, Radoslav, Ben-Nissan, Gili, Levin, Yishai, Kupervaser, Meital, Friedlander, Gilgi, Salame, Tomer Meir, Nevo, Reinat, Peter, Matthias, Sharon, Michal
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206152/
https://ncbi.nlm.nih.gov/pubmed/31367012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0392-8
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