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LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases
Leucine zipper-like transcriptional regulator 1 (LZTR1) encodes a member of the BTB-Kelch superfamily, which interacts with the Cullin3 (CUL3)-based E3 ubiquitin ligase complex. Mutations in LZTR1 have been identified in glioblastoma, schwannomatosis, and Noonan syndrome. However, the functional rol...
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| Izdano u: | Cell Death Differ |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206011/ https://ncbi.nlm.nih.gov/pubmed/31337872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0395-5 |
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