Costello syndrome model mice with a Hras(G12S/+) mutation are susceptible to develop house dust mite-induced atopic dermatitis

Costello syndrome is an autosomal dominant disorder that is caused by germline HRAS mutations. Patients with Costello syndrome present craniofacial abnormalities, cardiac defects, and cancer predisposition, as well as skin abnormalities, including papillomas, keratosis pilaris, and eczematous dermat...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Katata, Yu, Inoue, Shin-ichi, Asao, Atsuko, Kobayashi, Shuhei, Terui, Hitoshi, Inoue-Shibui, Aya, Abe, Taiki, Niihori, Tetsuya, Aiba, Setsuya, Ishii, Naoto, Kure, Shigeo, Aoki, Yoko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426869/
https://ncbi.nlm.nih.gov/pubmed/32792500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02845-8
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